Abbreviated name: PAO
Synonyms: arzene | oxophenylarsine | PAO | phenylarsenoxide
Compound class:
Synthetic organic
Comment: PAO inhibits type III PI 4-kinases, whereas it is relatively ineffective against the type II in in vitro kinase assays. Among the type III enzymes, PI4KIIIα is significantly more sensitive to PAO than the type IIIβ form [1].
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References |
1. Balla A, Tuymetova G, Barshishat M, Geiszt M, Balla T. (2002)
Characterization of type II phosphatidylinositol 4-kinase isoforms reveals association of the enzymes with endosomal vesicular compartments. J Biol Chem, 277 (22): 20041-50. [PMID:11923287] |