CC-885

Ligand id: 9224

Name: CC-885

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 107.61
Molecular weight 440.13
XLogP 1.94
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Matyskiela ME, Lu G, Ito T, Pagarigan B, Lu CC, Miller K, Fang W, Wang NY, Nguyen D, Houston J et al.. (2016)
A novel cereblon modulator recruits GSPT1 to the CRL4(CRBN) ubiquitin ligase.
Nature,  [Epub ahead of print]. [PMID:27338790]