AZ3146

Ligand id: 9400

Name: AZ3146

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 83.06
Molecular weight 452.25
XLogP 2.63
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Hewitt L, Tighe A, Santaguida S, White AM, Jones CD, Musacchio A, Green S, Taylor SS. (2010)
Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex.
J. Cell Biol.190 (1): 25-34. [PMID:20624899]