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Synonyms: compound 14 [PMID: 26819675]
Compound class:
Peptide or derivative
Comment: AY77 is a potent small molecule, peptidic PAR2 agonist [1]. The compound is stable in rat plasma making it suitable for physiological studies.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| References |
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1. Yau MK, Suen JY, Xu W, Lim J, Liu L, Adams MN, He Y, Hooper JD, Reid RC, Fairlie DP. (2016)
Potent Small Agonists of Protease Activated Receptor 2. ACS Med Chem Lett, 7 (1): 105-10. [PMID:26819675] |
