(-)-sulpiride

Ligand id: 958

Name: (-)-sulpiride

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 110.11
Molecular weight 341.14
XLogP 0.28
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Freedman SB, Patel S, Marwood R, Emms F, Seabrook GR, Knowles MR, McAllister G. (1994)
Expression and pharmacological characterization of the human D3 dopamine receptor.
J Pharmacol Exp Ther268: 417-426. [PMID:8301582]
2. Patel S, Patel S, Marwood R, Emms F, Marston D, Leeson PD, Curtis NR, Kulagowski JJ, Freedman SB. (1996)
Identification and pharmacological characterization of [125I]L-750,667, a novel radioligand for the dopamine D4 receptor.
Mol Pharmacol50: 1658-1664. [PMID:8967990]
3. Sokoloff P, Andrieux M, Besançon R, Pilon C, Martres M-P, Giros B, Schwartz J-C. (1992)
Pharmacology of human D3 dopamine receptor expressed in a mammalian cell line : comparison with D2 receptor.
Eur. J. Pharmacol.225: 331-337. [PMID:1354163]
4. Tang L, Todd RD, Heller A, O'Malley KL. (1994)
Pharmacological and functional characterization of D2, D3 and D4 dopamine receptors in fibroblast and dopaminergic cell lines.
J Pharmacol Exp Ther268: 495-502. [PMID:8301592]