amisulpride

Ligand id: 963

Name: amisulpride

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 110.11
Molecular weight 369.17
XLogP 1.53
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
1. Malmberg A, Jackson DM, Eriksson A, Mohell N. (1993)
Unique binding characteristics of antipsychotic agents interacting with human dopamine D2A, D2B, and D3 receptors.
Mol Pharmacol43: 749-754. [PMID:8099194]
2. Sokoloff P, Andrieux M, Besançon R, Pilon C, Martres M-P, Giros B, Schwartz J-C. (1992)
Pharmacology of human D3 dopamine receptor expressed in a mammalian cell line : comparison with D2 receptor.
Eur. J. Pharmacol.225: 331-337. [PMID:1354163]
3. Sokoloff P, Giros B, Martres MP, Bouthenet ML, Schwartz JC. (1990)
Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics.
Nature347: 146-151. [PMID:1975644]