sertindole

Ligand id: 98

Name: sertindole

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 40.51
Molecular weight 440.18
XLogP 4.22
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

References
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Atypical neuroleptics have low affinity for dopamine D2 receptors or are selective for D4 receptors.
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Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors.
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