Ligand Id: 134
Ligand name methysergide

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 57.5
Molecular weight 353.21
XLogP 1.47
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands

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Similar Ligands
lysergol
IUPHAR-DB targets
5-HT1B receptor; 5-HT1D receptor; 5-ht1e receptor
(+)-lysergic acid
IUPHAR-DB targets
5-HT1D receptor; 5-ht5a receptor
methylergonovine
IUPHAR-DB targets
5-HT1F receptor; 5-HT2A receptor; 5-HT2B receptor; 5-HT2C receptor; 5-ht1e receptor
[3H]LSD
GRAC targets
5-HT2B receptor; 5-HT2C receptor; 5-HT6 receptor; 5-HT7 receptor
IUPHAR-DB targets
5-HT2B receptor; 5-HT2C receptor; 5-HT6 receptor; 5-HT7 receptor
LSD
IUPHAR-DB targets
5-HT1A receptor; 5-HT2A receptor; 5-HT2B receptor; 5-HT2C receptor; 5-HT6 receptor
(+)-LSD
IUPHAR-DB targets
5-HT2A receptor; 5-HT2B receptor; 5-HT2C receptor; 5-HT7 receptor
ergonovine
IUPHAR-DB targets
5-HT2A receptor; 5-ht1e receptor
lisuride
IUPHAR-DB targets
α1A-adrenoceptor; α2A-adrenoceptor; α2B-adrenoceptor; α2C-adrenoceptor; 5-HT1A receptor; 5-HT1D receptor; 5-HT2A receptor; 5-HT2B receptor; 5-HT2C receptor; 5-HT6 receptor; 5-HT7 receptor; D2 receptor; D3 receptor; D5 receptor
beta-ergocriptine
IUPHAR-DB targets
D5 receptor
[125I]LSD
GRAC targets
5-HT1F receptor; 5-ht5a receptor; 5-ht5b receptor
IUPHAR-DB targets
5-HT1F receptor; 5-HT7 receptor; 5-ht5a receptor
ergotamine
IUPHAR-DB targets
5-HT1F receptor; 5-HT2A receptor; 5-HT2B receptor; 5-HT2C receptor; 5-HT6 receptor; 5-HT7 receptor; 5-ht1e receptor; 5-ht5a receptor
2-Br-LSD
IUPHAR-DB targets
5-HT6 receptor; 5-HT7 receptor
α-ergocryptine
IUPHAR-DB targets
5-HT6 receptor
apomorphine
IUPHAR-DB targets
α2A-adrenoceptor; α2B-adrenoceptor; α2C-adrenoceptor; 5-HT1A receptor; 5-HT2A receptor; 5-HT2B receptor; 5-HT2C receptor; D1 receptor; D2 receptor; D3 receptor; D4 receptor; D5 receptor
PD98059
fluperlapine
IUPHAR-DB targets
5-HT6 receptor; 5-HT7 receptor