Ligand Id: 1693
Ligand name SB 612111

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 23.47
Molecular weight 417.16
XLogP 6.82
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands

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Similar Ligands
TBPB
pimozide
IUPHAR-DB targets
5-HT1A receptor; 5-HT2A receptor; 5-HT6 receptor; 5-HT7 receptor; Cav3.1; Cav3.2; Cav3.3; D2 receptor; D3 receptor; H1 receptor; Kv1.8; Kir3.2
domperidone
GRAC targets
D2 receptor
IUPHAR-DB targets
D2 receptor; D3 receptor
L-779,976
IUPHAR-DB targets
sst2 receptor
L-054,522
GRAC targets
sst2 receptor
IUPHAR-DB targets
sst2 receptor
L-372662
GRAC targets
OT receptor
IUPHAR-DB targets
OT receptor
J-113397
GRAC targets
NOP receptor
IUPHAR-DB targets
NOP receptor
ketanserin
GRAC targets
5-HT2A receptor; Vesicular monoamine transporter 1; Vesicular monoamine transporter 2
IUPHAR-DB targets
α1A-adrenoceptor; α1B-adrenoceptor; α1D-adrenoceptor; 5-HT1B receptor; 5-HT1D receptor; 5-HT2A receptor; 5-HT2B receptor; 5-HT2C receptor; 5-HT7 receptor; D1 receptor; D5 receptor
[3H]ketanserin
GRAC targets
5-HT2A receptor
IUPHAR-DB targets
5-HT2A receptor
[35S]non-peptide OT antagonist
GRAC targets
OT receptor
IUPHAR-DB targets
OT receptor
AF-DX 116
GRAC targets
M1 receptor; M2 receptor; M3 receptor; M4 receptor; M5 receptor
IUPHAR-DB targets
M1 receptor; M2 receptor; M3 receptor; M4 receptor; M5 receptor
[18F]altanserin
GRAC targets
5-HT2A receptor
IUPHAR-DB targets
5-HT2A receptor
guanylpirenzepine
GRAC targets
M1 receptor; M2 receptor; M3 receptor; M4 receptor; M5 receptor
IUPHAR-DB targets
M1 receptor; M2 receptor; M3 receptor; M4 receptor