Ligand Id: 1881
Ligand name PGD2

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 12
Topological polar surface area 94.83
Molecular weight 352.22
XLogP 2.9
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands Radio analogues

For advanced searching click here to open chemical structure editor

Similar Ligands
19(R)-OH-PGE2
IUPHAR-DB targets
EP2 receptor; EP4 receptor
PGE2
GRAC targets
DP1 receptor; DP2 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; IP1 receptor; Organic anion transporter 2; Organic cation transporter 1; Organic cation transporter 2; TP receptor
IUPHAR-DB targets
DP1 receptor; DP2 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; IP1 receptor; TP receptor
[3H]PGE2
GRAC targets
EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; OATP2A1; OATP3A1
IUPHAR-DB targets
DP1 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor
17-phenyl-ω-trinor-PGE2
GRAC targets
EP1 receptor
IUPHAR-DB targets
EP1 receptor; EP2 receptor; EP3 receptor
1-OH-PGE1
IUPHAR-DB targets
EP4 receptor
16,16-dimethyl-PGE2
IUPHAR-DB targets
EP2 receptor; EP3 receptor; EP4 receptor
11-deoxy-PGE2
IUPHAR-DB targets
EP4 receptor
[3H]PGD2
GRAC targets
DP1 receptor; DP2 receptor
IUPHAR-DB targets
DP1 receptor; DP2 receptor
PGE1
IUPHAR-DB targets
DP1 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; IP1 receptor
sulprostone
GRAC targets
EP3 receptor
IUPHAR-DB targets
EP1 receptor; EP3 receptor; FP receptor
PGD3
IUPHAR-DB targets
DP2 receptor
ONO-AE-248
GRAC targets
EP3 receptor
IUPHAR-DB targets
EP2 receptor; EP3 receptor
11-dehydro-thromboxane B2
IUPHAR-DB targets
DP2 receptor
15(S)-15-methyl-PGD2
IUPHAR-DB targets
DP2 receptor
15(R)-15-methyl-PGD2
GRAC targets
DP2 receptor
IUPHAR-DB targets
DP2 receptor
PGJ2
IUPHAR-DB targets
DP1 receptor; DP2 receptor
isocarbacyclin
IUPHAR-DB targets
EP2 receptor; EP3 receptor; IP1 receptor
TEI-9063
IUPHAR-DB targets
IP1 receptor
CTA2
IUPHAR-DB targets
TP receptor
enprostil
IUPHAR-DB targets
EP1 receptor; EP3 receptor; EP4 receptor; FP receptor
11-deoxy-PGE1
IUPHAR-DB targets
EP2 receptor; EP3 receptor; EP4 receptor
ONO-DI-004
GRAC targets
EP1 receptor
IUPHAR-DB targets
EP1 receptor
PGH2
GRAC targets
CYP5A1; TP receptor
IUPHAR-DB targets
TP receptor
U46609
IUPHAR-DB targets
TP receptor
PGI2
GRAC targets
DP1 receptor; DP2 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; IP1 receptor; TP receptor
IUPHAR-DB targets
DP1 receptor; DP2 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; IP1 receptor; TP receptor
U46619
GRAC targets
TP receptor
IUPHAR-DB targets
DP1 receptor; DP2 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; TP receptor
[3H]U46619
IUPHAR-DB targets
TP receptor
13,14-dihydro-15-keto-PGD2
GRAC targets
DP2 receptor
IUPHAR-DB targets
DP2 receptor
misoprostol (free acid form)
IUPHAR-DB targets
EP2 receptor; EP3 receptor; EP4 receptor
carbacyclin
IUPHAR-DB targets
DP1 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; IP1 receptor; TP receptor
bimatoprost
IUPHAR-DB targets
FP receptor
15-deoxy-Δ12,14-PGD2
IUPHAR-DB targets
DP2 receptor
PGF1α
ONO-AE1-329
GRAC targets
EP4 receptor
IUPHAR-DB targets
EP2 receptor; EP3 receptor; EP4 receptor
PGF2-1-ethanolamide
GR 63799
IUPHAR-DB targets
EP3 receptor
AFP-07
GRAC targets
IP1 receptor
IUPHAR-DB targets
IP1 receptor
13,14-dihydro-PGE1
IUPHAR-DB targets
EP4 receptor
ONO-4819
IUPHAR-DB targets
EP2 receptor; EP3 receptor; EP4 receptor
misoprostol (methyl ester)
IUPHAR-DB targets
EP2 receptor; EP3 receptor; EP4 receptor
M&B 28767
IUPHAR-DB targets
EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; TP receptor
latanoprost (isopropyl ester)
IUPHAR-DB targets
FP receptor
SC46275
GRAC targets
EP3 receptor
IUPHAR-DB targets
EP3 receptor
butaprost
AGN192093
IUPHAR-DB targets
TP receptor