Ligand Id: 206
Ligand name mesulergine

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 53.93
Molecular weight 361.18
XLogP 2.1
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands Radio analogues

For advanced searching click here to open chemical structure editor

Similar Ligands
LY86057
IUPHAR-DB targets
5-HT2A receptor; 5-HT2B receptor
LY108742
IUPHAR-DB targets
5-HT2A receptor
LY53857
IUPHAR-DB targets
5-HT2A receptor; 5-HT2B receptor
terguride
IUPHAR-DB targets
α1A-adrenoceptor; α2A-adrenoceptor; α2B-adrenoceptor; α2C-adrenoceptor; 5-HT1A receptor; 5-HT1B receptor; 5-HT1D receptor; 5-HT2A receptor; 5-HT2B receptor; 5-HT2C receptor; D2 receptor; D3 receptor; D4 receptor
dihydroergocryptine
IUPHAR-DB targets
5-HT7 receptor
dihydroergocristine
IUPHAR-DB targets
5-HT6 receptor
dihydroergotamine
IUPHAR-DB targets
5-HT1B receptor; 5-HT1D receptor; 5-HT1F receptor; 5-HT6 receptor; 5-HT7 receptor; 5-ht1e receptor
cabergoline
IUPHAR-DB targets
α1A-adrenoceptor; α2A-adrenoceptor; α2B-adrenoceptor; α2C-adrenoceptor; 5-HT1A receptor; 5-HT1B receptor; 5-HT1D receptor; 5-HT2A receptor; 5-HT2B receptor; 5-HT2C receptor; D1 receptor; D2 receptor; D3 receptor; D4 receptor; D5 receptor... click on ligand to see complete list
sergolexole
IUPHAR-DB targets
5-HT2A receptor
LY215840
IUPHAR-DB targets
5-HT2A receptor
amesergide
IUPHAR-DB targets
5-HT2A receptor; 5-HT2B receptor
pergolide
IUPHAR-DB targets
α2A-adrenoceptor; α2B-adrenoceptor; α2C-adrenoceptor; 5-HT1A receptor; 5-HT1B receptor; 5-HT1D receptor; 5-HT2A receptor; 5-HT2B receptor; 5-HT6 receptor; 5-HT7 receptor; D1 receptor; D2 receptor; D3 receptor; D4 receptor; D5 receptor... click on ligand to see complete list
cyclopiazonic acid
lergotrile
IUPHAR-DB targets
5-HT6 receptor
CI-1015
IUPHAR-DB targets
CCK1 receptor; CCK2 receptor
[125I]PD142308
GRAC targets
CCK2 receptor
PD-135666
IUPHAR-DB targets
CCK2 receptor
PD-140548
GRAC targets
CCK1 receptor
IUPHAR-DB targets
CCK1 receptor; CCK2 receptor
SRA880
GRAC targets
sst1 receptor
IUPHAR-DB targets
sst1 receptor
[3H]PD140376
GRAC targets
CCK2 receptor
IUPHAR-DB targets
CCK2 receptor
[3H]mesulergine
GRAC targets
5-HT2B receptor; 5-HT2C receptor
IUPHAR-DB targets
5-HT2C receptor
[11C]DTBZ
GRAC targets
Vesicular monoamine transporter 2
metergoline
IUPHAR-DB targets
5-HT1B receptor; 5-HT1D receptor; 5-HT1F receptor; 5-HT2A receptor; 5-HT2B receptor; 5-HT2C receptor; 5-HT6 receptor; 5-HT7 receptor; 5-ht1e receptor; 5-ht5a receptor
(+)-butaclamol
IUPHAR-DB targets
5-HT1A receptor; 5-HT2A receptor; 5-HT7 receptor; D1 receptor; D2 receptor; D3 receptor; D4 receptor; D5 receptor
S3969
GRAC targets
ENaCαβγ
bromocriptine
IUPHAR-DB targets
α2A-adrenoceptor; α2B-adrenoceptor; α2C-adrenoceptor; 5-HT1A receptor; 5-HT1B receptor; 5-HT1D receptor; 5-HT2A receptor; 5-HT2B receptor; 5-HT6 receptor; 5-HT7 receptor; D2 receptor; D3 receptor; D4 receptor
LS-192629
IUPHAR-DB targets
OT receptor; V1A receptor
ACT-078573
IUPHAR-DB targets
OX1 receptor; OX2 receptor
SR58611A
IUPHAR-DB targets
β3-adrenoceptor
N-acyl 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
GRAC targets
OX2 receptor
IUPHAR-DB targets
OX2 receptor
N1-(2-Phenylethyl)-2R)-2-{[4-chorobenzoyl)-hydrazino] carboxamido}3-(1H-3-indolyl)propanamide
IUPHAR-DB targets
BB3 receptor
UBP141
GRAC targets
GluN2A; GluN2B; GluN2C; GluN2D