[3H]dexamethasone

Ligand id: 3447

Name: [3H]dexamethasone    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 94.83
Molecular weight 392.2
XLogP 1.14
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

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Similar Ligands
chenodeoxycholic acid
Targets
FPR1; Farnesoid X receptor; GPBA receptor
cholic acid
Targets
Farnesoid X receptor; GPBA receptor; Sodium/bile acid and sulphated solute cotransporter 1; Sodium/bile acid and sulphated solute cotransporter 2
deoxycholic acid
Targets
FPR1; Farnesoid X receptor; GPBA receptor
lithocholic acid
Targets
Farnesoid X receptor; GPBA receptor; Pregnane X receptor; Vitamin D receptor
dehydroepiandrosterone
Targets
Glycine Receptor (All subtypes)
pregnenolone
Targets
Glycine Receptor (All subtypes)
RU5135
Targets
Glycine Receptor (All subtypes)
bardoxolone
Targets
Peroxisome proliferator-activated receptor-γ; kelch like ECH-associated protein 1
cholesterol
Targets
RAR-related orphan receptor-α
22R-hydroxycholesterol
Targets
Farnesoid X receptor; Liver X receptor-α; Liver X receptor-β
lanosterol
Targets
Farnesoid X receptor-β
vitamin D3
Targets
Farnesoid X receptor-β
desmosterol
Targets
Farnesoid X receptor-β; Liver X receptor-α; Liver X receptor-β
24(S)-hydroxycholesterol
Targets
Liver X receptor-α; Liver X receptor-β
24(S), 25-epoxycholesterol
Targets
Liver X receptor-α; Liver X receptor-β
27-hydroxycholesterol
Targets
GPR183; Liver X receptor-α; Liver X receptor-β
androstenol
Targets
Constitutive androstane receptor
pregnenolone-16α-carbonitrile
Targets
Pregnane X receptor
hyperforin
Targets
Pregnane X receptor; TRPC6
dexamethasone
Targets
Glucocorticoid receptor; Mineralocorticoid receptor; Pregnane X receptor
2MD
Targets
Vitamin D receptor
seocalcitol
Targets
Vitamin D receptor
calcipotriol
Targets
Vitamin D receptor
1,25-dihydroxyvitamin D3
Targets
Vitamin D receptor
tacalcitol
Targets
Vitamin D receptor
falecalcitriol
Targets
Vitamin D receptor
gemini
Targets
Vitamin D receptor
elocalcitol
Targets
Vitamin D receptor
doxercalciferol
Targets
Vitamin D receptor
paricalcitol
Targets
Vitamin D receptor
mifepristone
Targets
Androgen receptor; Glucocorticoid receptor; Pregnane X receptor; Progesterone receptor
toxaphene
Targets
Estrogen-related receptor-α
dihydrotestosterone
Targets
Androgen receptor
methyltrienolone
Targets
Androgen receptor
testosterone
Targets
Androgen receptor
mibolerone
Targets
Androgen receptor
fluoxymesterone
Targets
Androgen receptor
prednisolone
Targets
Glucocorticoid receptor; Mineralocorticoid receptor
cortisol
Targets
Glucocorticoid receptor; Mineralocorticoid receptor
corticosterone
Targets
Glucocorticoid receptor; Mineralocorticoid receptor
triamcinolone
Targets
Glucocorticoid receptor
aldosterone
Targets
Glucocorticoid receptor; Mineralocorticoid receptor
fludrocortisone
Targets
Mineralocorticoid receptor
medroxyprogesterone
Targets
Progesterone receptor
norethisterone
Targets
Progesterone receptor
levonorgestrel
Targets
Progesterone receptor
onapristone
Targets
Glucocorticoid receptor; Mineralocorticoid receptor; Progesterone receptor
asoprisnil
Targets
Progesterone receptor
25-hydroxycholesterol
Targets
GPR183; Liver X receptor-α; Liver X receptor-β; RAR-related orphan receptor-γ
compound 18 [PMID: 8426367]
Targets
hydroxymethylglutaryl-CoA reductase
oleanolic acid
Targets
GPBA receptor
7-hydroxycholesterol
Targets
RAR-related orphan receptor-α
20S-hydroxycholesterol
Targets
Liver X receptor-α; Liver X receptor-β
obeticholic acid
Targets
Farnesoid X receptor
CDDO-Me
Targets
Peroxisome proliferator-activated receptor-γ
RU28362
Targets
Glucocorticoid receptor
RU26988
Targets
Glucocorticoid receptor
ZK112993
Targets
Glucocorticoid receptor; Mineralocorticoid receptor; Progesterone receptor
deoxycortisone
Targets
Glucocorticoid receptor
RU28318
Targets
Mineralocorticoid receptor
[3H]aldosterone
Targets
Mineralocorticoid receptor
[3H]dihydrotestosterone
Targets
Androgen receptor
[3H]mibolerone
Targets
Androgen receptor
[3H]methyltrienolone
Targets
Androgen receptor
betulinic acid
Targets
GPBA receptor
5α-pregnan-3α-ol-20-one
Targets
GABAA receptor α1 subunit; GABAA receptor α2 subunit; GABAA receptor α3 subunit; GABAA receptor α4 subunit; GABAA receptor α5 subunit; GABAA receptor α6 subunit
tetrahydrodeoxycorticosterone
Targets
GABAA receptor α1 subunit; GABAA receptor α2 subunit; GABAA receptor α3 subunit; GABAA receptor α4 subunit; GABAA receptor α5 subunit; GABAA receptor α6 subunit
7α,25-dihydroxycholesterol
Targets
GPR183
7α-hydroxycholesterol
Targets
GPR183
7β-hydroxycholesterol
Targets
GPR183
7α,27-dihydroxycholesterol
Targets
GPR183
7β, 27-dihydroxycholesterol
Targets
GPR183
7β, 25-dihydroxycholesterol
Targets
GPR183
11-deoxycortisol
17α-hydroxypregnenolone
17α-hydroxyprogesterone
cortisone
alphaxalone
abiraterone
Targets
CYP17A1
calcifediol
methyltestosterone
Targets
Androgen receptor
ethylestrenol
Targets
Androgen receptor
nandrolone
Targets
Androgen receptor
nahuoic acid A
Targets
lysine methyltransferase 5A
S-EMCA
Targets
GPBA receptor
beclometasone
Targets
Glucocorticoid receptor
betamethasone
Targets
Glucocorticoid receptor
desogestrel
desoximetasone
Targets
Glucocorticoid receptor
fluorometholone
Targets
Glucocorticoid receptor
medrysone
methylprednisolone
Targets
Glucocorticoid receptor; TRPC5
prednisone
Targets
Glucocorticoid receptor
rimexolone
ursodeoxycholic acid
ulipristal acetate
Targets
Progesterone receptor
etonogestrel
dienogest
inecalcitol
Targets
Vitamin D receptor
APR19
Targets
Progesterone receptor
compound 5 [PMID: 10869194]
Targets
PLCγ1
3beta-Hydroxy-20(29)-lupene
mometasone
Targets
Glucocorticoid receptor
clobetasone
megestrol
vamorolone
Targets
Glucocorticoid receptor
rosiptor
Targets
INPP5D
tibolone
Targets
Estrogen receptor-α