Ligand Id: 3635
Ligand name N-arachidonoylglycine

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 17
Topological polar surface area 66.4
Molecular weight 361.26
XLogP 7.52
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands

For advanced searching click here to open chemical structure editor

Similar Ligands
N-arachidonyl-γ-aminobutyric acid
anandamide
GRAC targets
α1; GPR119; N-Acylethanolamine acid amidase; Fatty acid amide hydrolase-1; Fatty acid amide hydrolase-2; K2P3.1; K2P9.1; Monoacylglycerol lipase; TRPM8; TRPV1
IUPHAR-DB targets
GPR119; GPR18; GPR55; N-Acylethanolamine acid amidase; CB1 receptor; CB2 receptor; Cav3.1; Cav3.2; Cav3.3; Fatty acid amide hydrolase-1; Fatty acid amide hydrolase-2; Glycine Receptor (All subtypes); Monoacylglycerol lipase; TRPV1
N-docosatetra-7,10,13,16-enoylethanolamine
N-homo-γ-linolenoylethanolamine
arachidonyl-2-chloroethylamide
GRAC targets
CB1 receptor
IUPHAR-DB targets
CB1 receptor
arachidonic acid
GRAC targets
15-LOX-1; 15-LOX-2; 5-LOX; COX-1 ; COX-2 ; ClC-2; Fatty acid transport protein 1; Fatty acid transport protein 4; K2P10.1; K2P18.1; K2P4.1; Maxi Cl-; TRPC6; TRPM2; protein kinase C, zeta... click on ligand to see complete list
IUPHAR-DB targets
Fatty acid transport protein 1; Fatty acid transport protein 4; Kv4.2; Kir2.3; Kir3.4; TRPM2; protein kinase C, zeta
N-arachidonyl-glycine
linoleic acid
GRAC targets
15-LOX-1; FFA1 receptor; Hepatocyte nuclear factor-4-α; TRPM8
IUPHAR-DB targets
FFA1 receptor; FFA4 receptor; Kv2.1; Peroxisome proliferator-activated receptor-γ
methyl arachidonate
GRAC targets
12R-LOX
γ-linolenic acid
GRAC targets
Fatty acid transport protein 1; Fatty acid transport protein 4; Fatty acid transport protein 6
IUPHAR-DB targets
Fatty acid transport protein 1; Fatty acid transport protein 4; Fatty acid transport protein 6
oleoylethanolamide
GRAC targets
GPR119; N-Acylethanolamine acid amidase; Fatty acid amide hydrolase-1; Fatty acid amide hydrolase-2
IUPHAR-DB targets
GPR119; GPR55; N-Acylethanolamine acid amidase; Fatty acid amide hydrolase-1; Fatty acid amide hydrolase-2; Peroxisome proliferator-activated receptor-α
arvanil
IUPHAR-DB targets
TRPV1
NADA
GRAC targets
TRPM8; TRPV1
arachidonyl cyclopropylamide
GRAC targets
CB1 receptor
IUPHAR-DB targets
GPR18; CB1 receptor
oleic acid
GRAC targets
Fatty acid transport protein 1; Fatty acid transport protein 4; Fatty acid transport protein 6; PLD2
IUPHAR-DB targets
FFA1 receptor; Fatty acid transport protein 1; Fatty acid transport protein 4; Fatty acid transport protein 6
R-(+)-methanandamide
GRAC targets
CB1 receptor
IUPHAR-DB targets
CB1 receptor
2-arachidonoylglycerol
GRAC targets
Monoacylglycerol lipase
IUPHAR-DB targets
GPR55; CB1 receptor; CB2 receptor; Monoacylglycerol lipase
olvanil
GRAC targets
TRPV1
IUPHAR-DB targets
GPR119; TRPV1
α-linolenic acid
IUPHAR-DB targets
FFA1 receptor; FFA4 receptor
EPA
GRAC targets
chemerin receptor
IUPHAR-DB targets
chemerin receptor
ATFMK
20-HETE
GRAC targets
TRPC6
N-arachidonyl-D-alanine
SAG
IUPHAR-DB targets
TRPC2; TRPC6
SLG
IUPHAR-DB targets
TRPC6
2-oleoyl glycerol
GRAC targets
Monoacylglycerol lipase
IUPHAR-DB targets
GPR119; Monoacylglycerol lipase
MEA
GRAC targets
N-Acylethanolamine acid amidase
IUPHAR-DB targets
N-Acylethanolamine acid amidase
N-palmitoylethanolamine
GRAC targets
GPR119; N-Acylethanolamine acid amidase; Fatty acid amide hydrolase-1; Fatty acid amide hydrolase-2
IUPHAR-DB targets
GPR119; N-Acylethanolamine acid amidase; Fatty acid amide hydrolase-1; Fatty acid amide hydrolase-2
SEA
GRAC targets
GPR119; N-Acylethanolamine acid amidase
IUPHAR-DB targets
GPR119; N-Acylethanolamine acid amidase
oleamide
GRAC targets
Fatty acid amide hydrolase-1; Fatty acid amide hydrolase-2
IUPHAR-DB targets
5-HT7 receptor; Fatty acid amide hydrolase-1; Fatty acid amide hydrolase-2
OMPT
GRAC targets
LPA3 receptor
IUPHAR-DB targets
LPA3 receptor
OAG
IUPHAR-DB targets
TRPC2; TRPC3; TRPC6; TRPC7
docosahexaenoic acid
GRAC targets
COX-2
IUPHAR-DB targets
FFA1 receptor; Retinoid X receptor-α
LPA
GRAC targets
GPR35; GPR87; P2RY10
IUPHAR-DB targets
GPR35; GPR87; P2RY10; LPA1 receptor; LPA2 receptor; LPA3 receptor; LPA4 receptor; LPA5 receptor; LPA6 receptor; S1P1 receptor
[3H]LPA
lysophosphatidylinositol
GRAC targets
GPR55
IUPHAR-DB targets
GPR119; GPR55
α-fluoromethylenephosphonate
IUPHAR-DB targets
LPA3 receptor
stearic acid
palmitic acid
GRAC targets
Fatty acid transport protein 1; Fatty acid transport protein 4; Fatty acid transport protein 6
IUPHAR-DB targets
FFA1 receptor; Fatty acid transport protein 1; Fatty acid transport protein 4; Fatty acid transport protein 6
octanoic acid
GRAC targets
Fatty acid transport protein 1; Fatty acid transport protein 4; Fatty acid transport protein 6
IUPHAR-DB targets
Fatty acid transport protein 1; Fatty acid transport protein 4; Fatty acid transport protein 6
O-1812
GRAC targets
CB1 receptor
IUPHAR-DB targets
CB1 receptor
VPC12249
IUPHAR-DB targets
LPA1 receptor; LPA3 receptor; S1P3 receptor
capsaicin
GRAC targets
CFTR; TRPV1
IUPHAR-DB targets
Kv1.1; Kv1.7; Kv3.1; TRPV1
VPC32183
IUPHAR-DB targets
LPA1 receptor; LPA3 receptor