10,10-difluoro TXA2

Ligand id: 6069

Name: 10,10-difluoro TXA2

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 12
Topological polar surface area 66.76
Molecular weight 386.23
XLogP 5.1
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

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Similar Ligands
16-HETE
15S-HETE
Targets
BLT2 receptor
9-hydroxyoctadecadienoic acid
Targets
GPR132
5S-HETE
Targets
OXE receptor; TRPV1
13-HODE
12-hydroxyheptadecatrienoic acid
Targets
BLT2 receptor
[3H]LTB4
Targets
BLT1 receptor; BLT2 receptor
LTB4
Targets
BLT1 receptor; BLT2 receptor; Peroxisome proliferator-activated receptor-α; TRPV1
12-epi LTB4
Targets
BLT2 receptor
12S-HETE
Targets
GPR31; BLT2 receptor
12S-[3H]HETE
Targets
GPR31
8S-HETE
Targets
Peroxisome proliferator-activated receptor-α
12R-HETE
Targets
BLT1 receptor; BLT2 receptor
15-deoxy-LXA4
Targets
FPR2/ALX
18S-HEPE
18R-HEPE
Targets
chemerin receptor
18-HETE
5-oxo-15-HETE
Targets
OXE receptor
LXB4
[3H]resolvin E1
Targets
chemerin receptor
18S-resolvin E1
resolvin E1
Targets
chemerin receptor
LXA4
Targets
GPR32; FPR2/ALX; FPR3
aspirin triggered lipoxin A4
Targets
FPR2/ALX
5-oxo-12-HETE
Targets
OXE receptor
carbocyclic thromboxane A2
Targets
TP receptor
prostaglandin A2
Targets
TRPA1
PGJ2
Targets
DP1 receptor; DP2 receptor
9α,11β-prostaglandin F
PGF
Targets
DP1 receptor; DP2 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; IP receptor; Organic cation transporter 1; TP receptor
20-hydroxy-LTB4
Targets
BLT1 receptor; BLT2 receptor
PGE2
Targets
DP1 receptor; DP2 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; IP receptor; OATP1A2; Organic anion transporter 2; Organic cation transporter 1; Organic cation transporter 2; TP receptor
11-deoxy-PGE2
Targets
EP4 receptor
[3H]PGE2
Targets
DP1 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; OATP2A1; OATP3A1
PGD2
Targets
DP1 receptor; DP2 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; IP receptor; TP receptor
[3H]PGD2
Targets
DP1 receptor; DP2 receptor
hepoxilin A3
[3H]LXA4
Targets
FPR2/ALX
aspirin-triggered resolvin D1
Targets
FPR2/ALX; TRPV3
resolvin D2
Targets
TRPA1
[3H]resolvin D1
Targets
GPR32
resolvin D1
Targets
GPR32; FPR2/ALX; TRPA1
11-deoxy-PGE1
Targets
EP2 receptor; EP3 receptor; EP4 receptor
PGF
Targets
CatSper1; CatSper2; CatSper3; CatSper4
U46619
Targets
DP1 receptor; DP2 receptor; EP1 receptor; EP2 receptor; EP3 receptor; EP4 receptor; FP receptor; TP receptor
[3H]U46619
Targets
TP receptor
U46609
Targets
TP receptor
PGH2
Targets
TP receptor
vigabatrin
Targets
4-aminobutyrate aminotransferase; Proton-coupled Amino acid Transporter 1; Vesicular inhibitory amino acid transporter
PGD3
Targets
DP2 receptor