Synonyms: BMY 41606 | CCRIS 6495 | RC 160 | RC-160 | Sanvar® | vapreotide acetate
vapreotide is an approved drug
Compound class:
Peptide or derivative
Comment: Vapreotide is a synthetic cyclic octapeptide analogue of somatostatin (like octreotide). It acts as predominantly as a somatostatin receptor SSTR-2/SSTR-5 agonist.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
Peptide Sequence | |
FCYWKVCW | |
H-DL-Phe-DL-Cys(1)-DL-Tyr-DL-Trp-DL-Lys-DL-Val-DL-Cys(1)-DL-Trp-NH2 |
HELM Notation | |
PEPTIDE1{(F,[dF]).(C,[dC]).(Y,[dY]).(W,[dW]).(K,[dK]).(V,[dV]).(C,[dC]).(W,[dW]).[am]}$PEPTIDE1,PEPTIDE1,2:R3-7:R3$$$V2.0 |
Chemical Modification | |
Amidation of C-terminal tryptophan, phenylalanine residue at position 1 and tryptophan residue at position 4 are D-Phe and D-Trp respectively; disulphide bridge between cysteine residues at positions 2 and 7 |
Download 2D Structure | |
Canonical SMILES | Download |
Isomeric SMILES | Download |
InChI standard identifier | Download |
InChI standard key | Download |
Molecular structure representations generated using Open Babel