[125I]Hpp-desArg10HOE140   Click here for help

GtoPdb Ligand ID: 3791

Synonyms: [125I]-Hpp-desArg9HOE140
 Ligand is labelled  Ligand is radioactive
Compound class: Peptide or derivative
Comment: Radiolabelled analogue of icatibant (HOE 140), a synthetic analogue of bradykinin.
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Peptide Sequence Click here for help
RRPXGXSXXR
3-4-hydroxyphenyl-propionyl-D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic
Chemical Modification
C-terminal arginine resdiue of the synthetic peptide HOE140 is removed; 3-4-hydroxyphenyl-propionyl-D-Arg is added to the N-terminus. X-4 = Hyp (4-Hydroxyproline), X-6 = Thi (3-Thienylalanine), X-8 = Tic (3-Carboxyisoquinoline), X-9 = Oic (2-Carboxyoctahydroindole)