thrombin heavy chain

Home
Ligands
thrombin heavy chain (Mouse)

GtoPdb Ligand ID: 4455

Synonyms: thrombin B chain (mouse)

Compound class: Endogenous peptide in human, mouse or rat

Species: Mouse

Summary
Biological activity
Structure
Similar ligands

Is a component of
thrombin

Is a component of

thrombin

Peptide Sequence
IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLLVRIGKHSRTRYERNVEKISM LEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVL QVVNLPIVERPVCKASTRIRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRKGKYGFY THVFRLKRWIQKVIDQFG

Post-translational Modification
Active mouse thrombin is a complex between thrombin light chain and thrombin heavy chain. The chains are linked by a disulphide bond between cysteine residues at position 9 of the light chain and 155 of the heavy chain. The heavy chain exhibits disulphide bond formation between cysteine residues at positions 28 and 44, 173 and 187, and 201 and 231; N-linked glycosylation of asparagine residues at positions 53 and 193

Post-translational Modification

Active mouse thrombin is a complex between thrombin light chain and thrombin heavy chain. The chains are linked by a disulphide bond between cysteine residues at position 9 of the light chain and 155 of the heavy chain.

The heavy chain exhibits disulphide bond formation between cysteine residues at positions 28 and 44, 173 and 187, and 201 and 231; N-linked glycosylation of asparagine residues at positions 53 and 193