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Synonyms: heat shock 60kD protein 1 (chaperonin) | HSP-60 | mitochondrial matrix protein P1
Compound class:
Endogenous peptide in human, mouse or rat
Comment: HSP60 is a mitochondrial chaperone that is upregulated by immune activation. It is a highly conserved protein, which acts as a major immune modulator in the control of the innate and adaptive immune systems in mammals [1-2].
Species: Human
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Peptide Sequence  |
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AKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTN EEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNII SDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEIANA HRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVG EVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALN ATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAM AGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMF |
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| Post-translational Modification | |
| Lysine residues at positions 5,56,99,104,107,176,192,243,326,333,370,443,447,497 are N6-acetyllysine; serine residue at position 44 is phosphoserine; tyrosine at position 201 is phosphotyrosine, and tyrosine residue at position 197 is predicted to be phosphotyrosine | |
