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Synonyms: α-calcitonin gene-related peptide (αCGRP, human) | calcitonin gene-related peptide 1 (CGRP)
Compound class:
Endogenous peptide in human, mouse or rat
Comment: This peptide is an isoform of calcitonin, encoded by the same gene and produced by alternative splicing. Please note that each peptide is represented by a different UniProt ID.
Species: Human
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖
View more information in the IUPHAR Pharmacology Education Project: α-cgrp |
Peptide Sequence  |
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| ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF | |
| Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2 | |
| Post-translational Modification | |
| Cysteine residues at positions 2 and 7 form a disulphide bridge and the C-terminal phenylalanine residue is amidated. | |
