crisantaspase   Click here for help

GtoPdb Ligand ID: 7347

Synonyms: asparaginase | Elspar® | L-asparaginase | L-asparagine amidohydrolase
Approved drug
crisantaspase is an approved drug (FDA (no history prior to 2011))
Compound class: Peptide or derivative
Comment: Crisantaspase is a chemotherapy agent. The asparaginase enzyme can be isolated from Erwinia chrysanthemi or Escherichia coli. The two forms have different immunogenicity profiles. The amino acid sequence shown here is for the Erwina isoform, crisantaspase.
Peptide Sequence Click here for help
ADKLPNIVILATGGTIAGSAATGTQTTGYKAGALGVDTLINAVPEVKKLANVKGEQFSNMASENMTGDVVLKLSQRVNEL
LARDDVDGVVITHGTDTVEESAYFLHLTVKSDKPVVFVAAMRPATAISADGPMNLLEAVRVAGDKQSRGRGVMVVLNDRI
GSARYITKTNASTLDTFKANEEGYLGVIIGNRIYYQNRIDKLHTTRSVFDVRGLTSLPKVDILYGYQDDPEYLYDAAIQH
GVKGIVYAGMGAGSVSVRGIAGMRKAMEKGVVVIRSTRTGNGIVPPDEELPGLVSDSLNPAHARILLMLALTRTSDPKVI
QEYFHTY