Synonyms: AZ-13337019 | AZ13337019 | Movantik® | Moventig® | NKTR-118
naloxegol is an approved drug (EMA & FDA (2014))
Compound class:
Synthetic organic
Comment: Naloxegol is a PEGylated version of naloxol (α-naloxol PubChem CID 5492271; β-naloxol PubChem CID 5492293). PEGylation reduces the compound's ability to cross the blood-brain barrier, therefore restricting CNS penetration. Naloxegol is termed a peripherally acting μ-opioid receptor antagonist, or PAMORA. The synonyms suffixed with "oxalate " map to the salt as PubChem CID 56959086
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Molecular structure representations generated using Open Babel