Synonyms: Duvroq® | GSK-1278863 | GSK1278863 | Jesduvroq®
daprodustat is an approved drug (Japan (2020), FDA (2023))
Compound class:
Synthetic organic
Comment: Daprodustat is a compound which inhibits hypoxia inducible factor prolyl hydroxylase (HIF-PH) activity. HIF-PH inhibitors are being investigated as novel therapies for anemia, especially anemia caused by chronic kindney disease (CKD). It is hoped that HIF-PH inhibitors will provide a more effective alternative to the use of erythropoetin replacement therapy plus iron supplementation in CKD patients
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Molecular structure representations generated using Open Babel