triptorelin   Click here for help

GtoPdb Ligand ID: 1177

Synonyms: CL 118532 | CL-118532 | Decapeptyl® | Pamorelin® | Trelstar® | Triptodur®
Approved drug
triptorelin is an approved drug (FDA (2001))
Compound class: Peptide or derivative
Comment: As is the case with many peptide molecules, there is some ambiguity as to the stereochemistry of triptorelin, therefore the chemical structure shown here may vary slightly from that displayed on the resources linked to from the table above. The marketed formulations contain triptorelin pamoate (PubChem CID 25074469) or triptorelin acetate (PubChem CID 25080282).
Click here for help

Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

✖

View interactive charts of activity data across species
2D Structure
Click here for help

2D Structure

An image of the ligand's 2D structure. For small molecules with SMILES these are drawn using the NCI/CADD Chemical Identifier Resolver. Click on the image to access the chemical structure search tool with the ligand pre-loaded in the structure editor. For other types of ligands, e.g. longer nucleotides and peptides, a manually drawn representation of the molecule may be provided.

✖
Click here for structure editor
SMILES / InChI / InChIKey
Click here for help

SMILES / InChI / InChIKey

SMILES (Simplified Molecular Input Line Entry Specification) A specification for unambiguously describing the structure of chemical molecules using short ASCII strings. Canonical SMILES specify a unique representation of the 2D structure without chiral or isotopic specifications. Isomeric SMILES include chiral specification and isotopes.

Standard InChI (IUPAC International Chemical Identifier) and InChIKey InChI is a non-proprietary, standard, textual identifier for chemical substances designed to facilitate linking of information and database searching. An InChIKey is a simplified version of a full InChI, designed for easier web searching.

✖
Canonical SMILES OCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1CCCC1C(=O)NCC(=O)N)CCCNC(=N)N)CC(C)C)Cc1c[nH]c2c1cccc2)Cc1ccc(cc1)O)NC(=O)C(Cc1c[nH]c2c1cccc2)NC(=O)C(NC(=O)C1CCC(=O)N1)Cc1nc[nH]c1
Isomeric SMILES OC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N)CCCNC(=N)N)CC(C)C)Cc1c[nH]c2c1cccc2)Cc1ccc(cc1)O)NC(=O)[C@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@@H](NC(=O)[C@@H]1CCC(=O)N1)Cc1nc[nH]c1
InChI InChI=1S/C64H82N18O13/c1-34(2)23-46(56(88)75-45(13-7-21-69-64(66)67)63(95)82-22-8-14-52(82)62(94)72-31-53(65)85)76-58(90)48(25-36-28-70-42-11-5-3-9-40(36)42)78-57(89)47(24-35-15-17-39(84)18-16-35)77-61(93)51(32-83)81-59(91)49(26-37-29-71-43-12-6-4-10-41(37)43)79-60(92)50(27-38-30-68-33-73-38)80-55(87)44-19-20-54(86)74-44/h3-6,9-12,15-18,28-30,33-34,44-52,70-71,83-84H,7-8,13-14,19-27,31-32H2,1-2H3,(H2,65,85)(H,68,73)(H,72,94)(H,74,86)(H,75,88)(H,76,90)(H,77,93)(H,78,89)(H,79,92)(H,80,87)(H,81,91)(H4,66,67,69)/t44-,45-,46-,47-,48+,49-,50-,51-,52-/m0/s1
InChI Key VXKHXGOKWPXYNA-PGBVPBMZSA-N
Classification Click here for help
Compound class Peptide or derivative
Approved drug? Yes (FDA (2001))
International Nonproprietary Names Click here for help
INN number INN
5711 triptorelin
Synonyms Click here for help
CL 118532 | CL-118532 | Decapeptyl® | Pamorelin® | Trelstar® | Triptodur®
Database Links Click here for help
Specialist databases
GPCRdb Ligand triptorelin
Other databases
CAS Registry No. 57773-63-4 (source: Scifinder)
ChEBI CHEBI:63633
ChEMBL Ligand CHEMBL1201334
DrugCentral Ligand 2968
GtoPdb PubChem SID 135652611
PubChem CID 25074470
Search Google for chemical match using the InChIKey VXKHXGOKWPXYNA-PGBVPBMZSA-N
Search Google for chemicals with the same backbone VXKHXGOKWPXYNA
Search PubMed clinical trials triptorelin
Search PubMed titles triptorelin
Search PubMed titles/abstracts triptorelin
UniChem Compound Search for chemical match using the InChIKey VXKHXGOKWPXYNA-PGBVPBMZSA-N
UniChem Connectivity Search for chemical match using the InChIKey VXKHXGOKWPXYNA-PGBVPBMZSA-N
Wikipedia Triptorelin