TRH

Ligand id: 2139

Name: TRH

Species: Human, Mouse, Rat

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View more information in the IUPHAR Pharmacology Education Project: trh

Structure and Physico-chemical Properties

2D Structure
Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Neuropeptides
Approved drug? Yes (FDA (1976))
IUPAC Name
(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(3H-imidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
International Nonproprietary Names
INN number INN
3335 protirelin
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
TRH thyrotropin releasing hormone Human thyrotropin-releasing hormone (Prothyroliberin) thyrotropin-releasing hormone
Trh thyrotropin releasing hormone Mouse thyrotropin-releasing hormone (Prothyroliberin) -
Trh thyrotropin releasing hormone Rat thyrotropin-releasing hormone (Prothyroliberin) prothyroliberin, THR, thyrotropin-releasing hormone, Thyrotropin releasing hormone, TRH01, Tryrotropin releasing hormone
Synonyms
thyroliberin
Database Links
CAS Registry No. 24305-27-9 (source: Scifinder)
ChEMBL Ligand CHEMBL1472
PubChem CID 638678
Search Google for chemical match using the InChIKey XNSAINXGIQZQOO-SRVKXCTJSA-N
Search Google for chemicals with the same backbone XNSAINXGIQZQOO
Search PubMed clinical trials protirelin
Search PubMed titles protirelin
Search PubMed titles/abstracts protirelin
Search UniChem for chemical match using the InChIKey XNSAINXGIQZQOO-SRVKXCTJSA-N
Search UniChem for chemicals with the same backbone XNSAINXGIQZQOO
UniProtKB P20396 (Hs), P01150 (Rn), Q62361 (Mm)
Wikipedia Thyrotropin-releasing_hormone
Comments
This structure matches the structure deposited with the INN record for protirelin, which is synthetic TRH.