oxytocin

Ligand id: 2174

Name: oxytocin

Abbreviated name: OT

Species: Human, Mouse, Rat

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Structure and Physico-chemical Properties

2D Structure
Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Neuropeptides
Approved drug? Yes (FDA (1980))
IUPAC Name
(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-[(2S)-butan-2-yl]-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
International Nonproprietary Names
INN number INN
1480 oxytocin
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
OXT oxytocin/neurophysin I prepropeptide Human prepro-OXT-NP I (prepro-oxytocin-neurophysin I) neurophysin I, OT, oxytocin, prepro- (neurophysin I), oxytocin, prepropeptide
Oxt oxytocin Mouse prepro-OXT-NP I (prepro-oxytocin-neurophysin I) Oxy
Oxt oxytocin/neurophysin 1 prepropeptide Rat prepro-OXT-NP I (prepro-oxytocin-neurophysin I) OT-NPI, oxcytocin, oxytocin, Oxytocin/neurophysin, oxytocin-neurophysin 1, oxytocin/neurophysin (Oxt) gene, complete gene, complete cds, oxytocin, prepropeptide, Rat oxytocin/neurophysin (Oxt) gene complete gene complete cds
Synonyms
Otx | Pitocin® | Syntocinon®
Database Links
CAS Registry No. 50-56-6
CATH/Gene3D 2.60.9.10
ChEBI CHEBI:7872
ChEMBL Ligand CHEMBL395429
DrugBank Ligand DB00107
GtoPdb PubChem SID 135651848
PubChem CID 439302
Search Google for chemical match using the InChIKey XNOPRXBHLZRZKH-DSZYJQQASA-N
Search Google for chemicals with the same backbone XNOPRXBHLZRZKH
Search PubMed clinical trials oxytocin
Search PubMed titles oxytocin
Search PubMed titles/abstracts oxytocin
Search UniChem for chemical match using the InChIKey XNOPRXBHLZRZKH-DSZYJQQASA-N
Search UniChem for chemicals with the same backbone XNOPRXBHLZRZKH
UniProtKB P01178 (Hs), P01179 (Rn), P35454 (Mm)
Wikipedia Oxytocin
Comments
Endogenous oxytocin is a hormone and neuropeptide, which plays a role in social bonding, sexual reproduction and is required during and after childbirth. Purified oxytocin is used clinically.