Ligand Id: 2341
Ligand name phorbol 12-myristate 13-acetate

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 17
Topological polar surface area 130.36
Molecular weight 616.4
XLogP 6.51
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands
Classification
Compound class Synthetic organic
IUPAC Name
(1S,2S,6R,10S,11R,13S,14R,15R)-13-(acetyloxy)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxotetracyclo[8.5.0.0^{2,6}.0^{11,13}]pentadeca-3,8-dien-14-yl tetradecanoate
Synonyms
12-O-tetradecanoylphorbol-13-acetate
PMA
tetradecanoyl-β-phorbol acetate
TPA
Database Links
BindingDB Ligand 50099066
CAS Registry No. 16561-29-8 (source: Scifinder)
ChEMBL Ligand 388401, 390655, 390826, 391290, 192809, 228763
PubChem CID 27924
Search on ChemSpider PHEDXBVPIONUQT-RGYGYFBISA-N
Wikipedia 12-O-Tetradecanoylphorbol-13-acetate
ZINC ZINC08214783
iPHACE 5NVUA1XF

Please note: some links may refer to related isomers. For more details please contact: curators@iuphar-db.org