verapamil

Ligand id: 2406

Name: verapamil

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: verapamil

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 13
Topological polar surface area 63.95
Molecular weight 454.28
XLogP 4.71
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1981))
IUPAC Name
2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile
International Nonproprietary Names
INN number INN
2122 verapamil
Synonyms
Ansyr® | CP-165331 / CP-16533-1 | Securon®
Database Links
BindingDB Ligand 50279753
CAS Registry No. 52-53-9
ChEBI CHEBI:9948
ChEMBL Ligand CHEMBL6966
DrugBank Ligand DB00661
PubChem CID 2520
Search Google for chemical match using the InChIKey SGTNSNPWRIOYBX-UHFFFAOYSA-N
Search Google for chemicals with the same backbone SGTNSNPWRIOYBX
Search PubMed clinical trials verapamil
Search PubMed titles verapamil
Search PubMed titles/abstracts verapamil
Search UniChem for chemical match using the InChIKey SGTNSNPWRIOYBX-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone SGTNSNPWRIOYBX
Wikipedia Verapamil
Comments
The approved drug verapamil is a racemic mixture of two enantiomers (PubChem CID 92305 and PubChem CID 65808). The structure shown here does not specify stereochemistry and represents the mixture. Marketed formulations may contain verapamil hydrochloride (PubChem CID 62969).