metoclopramide

Ligand id: 241

Name: metoclopramide

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 67.59
Molecular weight 299.14
XLogP 1.14
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1979))
IUPAC Name
4-amino-5-chloro-N-(2-diethylaminoethyl)-2-methoxybenzamide
International Nonproprietary Names
INN number INN
1740 metoclopramide
Synonyms
metaclopromide | methochlopramide | metochlopramide | metoclopramide hydrochloride | Reglan®
Database Links
BindingDB Ligand 50000491
CAS Registry No. 364-62-5 (source: Scifinder)
ChEBI CHEBI:107736
ChEMBL Ligand CHEMBL86
DrugBank Ligand DB01233
PubChem CID 4168
Search Google for chemical match using the InChIKey TTWJBBZEZQICBI-UHFFFAOYSA-N
Search Google for chemicals with the same backbone TTWJBBZEZQICBI
Search PubMed clinical trials metoclopramide
Search PubMed titles metoclopramide
Search PubMed titles/abstracts metoclopramide
Search UniChem for chemical match using the InChIKey TTWJBBZEZQICBI-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone TTWJBBZEZQICBI
Wikipedia Metoclopramide
Comments
Metoclopramide is a promarily dopamine receptor antagonist, but it also exhibits mixed 5-HT3 receptor antagonist/5-HT4 receptor agonist activity.