amiloride

Ligand id: 2421

Name: amiloride

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 4
Rotatable bonds 2
Topological polar surface area 159.29
Molecular weight 229.05
XLogP -1.18
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1981))
IUPAC Name
3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide
International Nonproprietary Names
INN number INN
2352 amiloride
Synonyms
amiloride HCl | Midamor®
Database Links
BindingDB Ligand 16173
CAS Registry No. 2609-46-3
ChEBI CHEBI:2639
ChEMBL Ligand CHEMBL945
DrugBank Ligand DB00594
PubChem CID 16231
RCSB PDB Ligand AMR
Search Google for chemical match using the InChIKey XSDQTOBWRPYKKA-UHFFFAOYSA-N
Search Google for chemicals with the same backbone XSDQTOBWRPYKKA
Search PubMed clinical trials amiloride
Search PubMed titles amiloride
Search PubMed titles/abstracts amiloride
Search UniChem for chemical match using the InChIKey XSDQTOBWRPYKKA-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone XSDQTOBWRPYKKA
Wikipedia Amiloride
Comments
Amiloride is a loop diuretic drug.