nisoldipine

Ligand id: 2524

Name: nisoldipine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 107.77
Molecular weight 388.16
XLogP 4.99
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1995))
IUPAC Name
O5-methyl O3-(2-methylpropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
International Nonproprietary Names
INN number INN
4753 nisoldipine
Synonyms
Sular®
Database Links
BindingDB Ligand 50011689
CAS Registry No. 63675-72-9 (source: Scifinder)
ChEMBL Ligand CHEMBL1726
DrugBank Ligand DB00401
PubChem CID 4499
Search Google for chemical match using the InChIKey VKQFCGNPDRICFG-UHFFFAOYSA-N
Search Google for chemicals with the same backbone VKQFCGNPDRICFG
Search PubMed clinical trials nisoldipine
Search PubMed titles nisoldipine
Search PubMed titles/abstracts nisoldipine
Search UniChem for chemical match using the InChIKey VKQFCGNPDRICFG-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone VKQFCGNPDRICFG
Wikipedia Nisoldipine
Comments
Nisoldipine is a dihydropyridine calcium channel blocker.