tamibarotene

Ligand id: 2648

Name: tamibarotene

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 66.4
Molecular weight 351.18
XLogP 7.28
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name
4-[(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]benzoic acid
International Nonproprietary Names
INN number INN
7349 tamibarotene
Synonyms
AM-80 | AM80 | Amnolake® | retinobenzoic acid
Database Links
BindingDB Ligand 50061625
CAS Registry No. 94497-51-5
ChEBI CHEBI:32181
ChEMBL Ligand CHEMBL25202
DrugBank Ligand DB04942
GtoPdb PubChem SID 135649930
PubChem CID 108143
RCSB PDB Ligand A80
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Wikipedia Tamibarotene
Comments
This compound is a retinoic acid receptor α (RARα) agonist [3].