Ligand Id: 2694
Ligand name pioglitazone

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 93.59
Molecular weight 356.12
XLogP 3.66
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands
Classification
Compound class Synthetic organic
Approved drug? Yes (source: DrugBank)
DrugBank groups approved; investigational
IUPAC Name
5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
International Nonproprietary Names
INN number INN
6343 pioglitazone
Database Links
BindingDB Ligand 50049240
CAS Registry No. 111025-46-8 (source: ChEBI)
ChEBI CHEBI:8228
ChEMBL Ligand 650857, 119737
DrugBank Ligand DB01132
NURSA Ligand 795
PharmGKB Drug PA450970
PubChem CID 4829
Search on ChemSpider HYAFETHFCAUJAY-UHFFFAOYSA-N
Wikipedia Pioglitazone
ZINC ZINC00968326, ZINC00968327

Please note: some links may refer to related isomers. For more details please contact: curators@iuphar-db.org