cyproheptadine

Ligand id: 277

Name: cyproheptadine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 0
Topological polar surface area 3.24
Molecular weight 287.17
XLogP 7.96
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1961))
IUPAC Name
1-methyl-4-{tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-ylidene}piperidine
International Nonproprietary Names
INN number INN
872 cyproheptadine
Synonyms
cyproheptidine | Periactin® | Peritol®
Database Links
BindingDB Ligand 50017721
CAS Registry No. 129-03-3
ChEBI CHEBI:111005
ChEMBL Ligand CHEMBL516
DrugBank Ligand DB00434
GtoPdb PubChem SID 135650152
PubChem CID 2913
RCSB PDB Ligand C7H
Search Google for chemical match using the InChIKey JJCFRYNCJDLXIK-UHFFFAOYSA-N
Search Google for chemicals with the same backbone JJCFRYNCJDLXIK
Search PubMed clinical trials cyproheptadine
Search PubMed titles cyproheptadine
Search PubMed titles/abstracts cyproheptadine
Search UniChem for chemical match using the InChIKey JJCFRYNCJDLXIK-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone JJCFRYNCJDLXIK
Wikipedia Cyproheptadine
Comments
Cyproheptadine is a histamine H1 receptor antagonist, and also antagonizes serotonin receptors.