rosuvastatin

Ligand id: 2954

Name: rosuvastatin

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 3
Rotatable bonds 10
Topological polar surface area 149.3
Molecular weight 481.17
XLogP 2.69
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2003))
IUPAC Name
(3R,5S)-7-[4-(4-fluorophenyl)-2-(methyl-methylsulfonylamino)-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid
International Nonproprietary Names
INN number INN
8021 rosuvastatin
Synonyms
Crestor® | ZD4522
Database Links
CAS Registry No. 287714-41-4 (source: Scifinder)
ChEBI CHEBI:38545
ChEMBL Ligand CHEMBL1496
DrugBank Ligand DB01098
PubChem CID 446157
Search Google for chemical match using the InChIKey BPRHUIZQVSMCRT-VEUZHWNKSA-N
Search Google for chemicals with the same backbone BPRHUIZQVSMCRT
Search PubMed clinical trials rosuvastatin
Search PubMed titles rosuvastatin
Search PubMed titles/abstracts rosuvastatin
Search UniChem for chemical match using the InChIKey BPRHUIZQVSMCRT-VEUZHWNKSA-N
Search UniChem for chemicals with the same backbone BPRHUIZQVSMCRT
Wikipedia Rosuvastatin
Comments
Marketed formulations may contain rosuvastatin calcium (PubChem CID 5282455).