dalvastatin

Ligand id: 3036

Name: dalvastatin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 46.53
Molecular weight 386.23
XLogP 6.74
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(4S,6R)-6-[(E)-2-[2-(4-fluoro-3-methylphenyl)-4,4,6,6-tetramethyl-1-cyclohexenyl]ethenyl]-4-hydroxyoxan-2-one
International Nonproprietary Names
INN number INN
6717 dalvastatin
Synonyms
RG 12561
Database Links
CAS Registry No. 132100-55-1
PubChem CID 6436002
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Comments
Dalvastatin is a synthetic inhibitor of HMG-CoA reductase with cholesterol-lowering activity [1] in vivo. The sodium salt is more active than the parent molecule in its ability to reduce the LDL/HDL ratio. Dalvastatin is a prodrug which converts to its open hydroxyacid form in the body.