darifenacin

Ligand id: 321

Name: darifenacin

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 55.56
Molecular weight 426.23
XLogP 7.59
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2004))
IUPAC Name
2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-di(phenyl)acetamide
International Nonproprietary Names
INN number INN
7153 darifenacin
Synonyms
Emselex® | Enablex® | UK-88525
Database Links
CAS Registry No. 133099-04-4
ChEBI CHEBI:391960
ChEMBL Ligand CHEMBL1346
DrugBank Ligand DB00496
PubChem CID 444031
Search Google for chemical match using the InChIKey HXGBXQDTNZMWGS-RUZDIDTESA-N
Search Google for chemicals with the same backbone HXGBXQDTNZMWGS
Search PubMed clinical trials darifenacin
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Search UniChem for chemical match using the InChIKey HXGBXQDTNZMWGS-RUZDIDTESA-N
Search UniChem for chemicals with the same backbone HXGBXQDTNZMWGS
Wikipedia Darifenacin
Comments
Darifenacin is a muscarinic acetylcholine M3 receptor antagonist.