zafirlukast

Ligand id: 3322

Name: zafirlukast

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 11
Topological polar surface area 124.11
Molecular weight 575.21
XLogP 5.83
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1996))
IUPAC Name
cyclopentyl N-{3-[(2-methoxy-4-{[(2-methylbenzene)sulfonyl]carbamoyl}phenyl)methyl]-1-methyl-1H-indol-5-yl}carbamate
International Nonproprietary Names
INN number INN
7244 zafirlukast
Synonyms
Accolate® | ICI-204219
Database Links
CAS Registry No. 107753-78-6 (source: Scifinder)
ChEMBL Ligand CHEMBL603
DrugBank Ligand DB00549
PubChem CID 5717
Search Google for chemical match using the InChIKey YEEZWCHGZNKEEK-UHFFFAOYSA-N
Search Google for chemicals with the same backbone YEEZWCHGZNKEEK
Search PubMed clinical trials zafirlukast
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Search UniChem for chemical match using the InChIKey YEEZWCHGZNKEEK-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone YEEZWCHGZNKEEK
Wikipedia Zafirlukast
Comments
Zafirlukast is an oral leukotriene receptor antagonist (LTRA), with selectivity for cysteinyl leukotriene receptor 1 (CysLT1 receptor).