Ligand Id: 3508
Ligand name darusentan

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Topological polar surface area 100
Molecular weight 410.15
XLogP 5.77
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands
Classification
Compound class Synthetic organic
IUPAC Name
(2S)-2-(4,6-dimethoxypyrimidin-2-yl)oxy-3-methoxy-3,3-di(phenyl)propanoic acid
International Nonproprietary Names
INN number INN
7838 darusentan
Synonyms
HMR-4005
Lu 135252
LU135252
LU-135252
(+)-(S)-2-(4,6-dimethoxypyrimidin-2-yloxy)-3-methoxy-3,3-propionic acid
Database Links
CAS Registry No. 171714-84-4 (source: Scifinder)
Search on ChemSpider FEJVSJIALLTFRP-LJQANCHMSA-N
Wikipedia Darusentan
ZINC ZINC03826221

Please note: some links may refer to related isomers. For more details please contact: curators@iuphar-db.org