amantidine

Ligand id: 4128

Name: amantidine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 26.02
Molecular weight 151.14
XLogP 2.31
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1966))
IUPAC Name
adamantan-1-amine
International Nonproprietary Names
INN number INN
1816 amantadine
Synonyms
ADS-5102 | Gocovri® | Symadine®
Database Links
CAS Registry No. 768-94-5 (source: Scifinder)
ChEBI CHEBI:2618
ChEMBL Ligand CHEMBL660
DrugBank Ligand DB00915
GtoPdb PubChem SID 178100950
PubChem CID 2130
Search Google for chemical match using the InChIKey DKNWSYNQZKUICI-UHFFFAOYSA-N
Search Google for chemicals with the same backbone DKNWSYNQZKUICI
Search PubMed clinical trials amantadine
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Search UniChem for chemical match using the InChIKey DKNWSYNQZKUICI-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone DKNWSYNQZKUICI
Wikipedia Amantidine
Comments
Chemically amantidine has an adamantane backbone with an amino group substituted at one of the four methyne positions. Clinically it has antiviral (blocking the viral M2 proton channel) and antiparkinsonian actions.