nomifensine

Ligand id: 4792

Name: nomifensine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 29.26
Molecular weight 238.15
XLogP 4.56
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (approval date not specified, withdrawn 1992))
Withdrawn drug? Yes
IUPAC Name
2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine
International Nonproprietary Names
INN number INN
2920 nomifensine
Synonyms
Alival® | Merital®
Database Links
CAS Registry No. 24526-64-5 (source: Scifinder)
ChEMBL Ligand CHEMBL273575
DrugBank Ligand DB04821
GtoPdb PubChem SID 178101494
PubChem CID 4528
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Search UniChem for chemical match using the InChIKey XXPANQJNYNUNES-UHFFFAOYSA-N
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Wikipedia Nomifensine
Comments
Nomifensine is a norepinephrine-dopamine reuptake inhibitor. Bioactivity is reported to lie with the (S) isomer.