folinic acid

Ligand id: 4816

Name: folinic acid

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 14
Hydrogen bond donors 8
Rotatable bonds 11
Topological polar surface area 215.22
Molecular weight 474.17
XLogP -3.67
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1952))
IUPAC Name
(2S)-2-[(4-{[(2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid
Synonyms
5-formyltetrahydrofolic acid | leucovorin | Wellcovorin®
Database Links
CAS Registry No. 58-05-9 (source: Scifinder)
ChEBI CHEBI:15640
ChEMBL Ligand CHEMBL1679
DrugBank Ligand DB00650
PubChem CID 6006
Search Google for chemical match using the InChIKey VVIAGPKUTFNRDU-ABLWVSNPSA-N
Search Google for chemicals with the same backbone VVIAGPKUTFNRDU
Search UniChem for chemical match using the InChIKey VVIAGPKUTFNRDU-ABLWVSNPSA-N
Search UniChem for chemicals with the same backbone VVIAGPKUTFNRDU
Wikipedia Folinic_acid
Comments
Folinic acid is the biologically active form of folic acid (also known as the (-)-l-isomer, citrovorum factor or (-)-folinic acid). The approved drug is called leucovorin.