zalcitabine

Ligand id: 4828

Name: zalcitabine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 87.82
Molecular weight 212.1
XLogP -0.69
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1992))
IUPAC Name
4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one
International Nonproprietary Names
INN number INN
6871 zalcitabine
Synonyms
dideoxycytidine (DDC) | Hivid® | Ro-242027000/Ro-24-2027-000
Database Links
CAS Registry No. 7481-89-2 (source: Scifinder)
ChEMBL Ligand CHEMBL853
DrugBank Ligand DB00943
PubChem CID 24066
Search Google for chemical match using the InChIKey WREGKURFCTUGRC-POYBYMJQSA-N
Search Google for chemicals with the same backbone WREGKURFCTUGRC
Search PubMed clinical trials zalcitabine
Search PubMed titles zalcitabine
Search PubMed titles/abstracts zalcitabine
Search UniChem for chemical match using the InChIKey WREGKURFCTUGRC-POYBYMJQSA-N
Search UniChem for chemicals with the same backbone WREGKURFCTUGRC
Wikipedia Zalcitabine
Comments
zalcitabine is a nucleoside analog reverse transcriptase inhibitor (NARTI) antiretroviral drug. Chemically it is an is an analogue of pyrimidine and is a derivative of endogenous deoxycytidine.