aciclovir

Ligand id: 4829

Name: aciclovir

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 4
Rotatable bonds 4
Topological polar surface area 114.43
Molecular weight 226.09
XLogP -1.83
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1982, prior history not available))
IUPAC Name
2-amino-9-[(2-hydroxyethoxy)methyl]-6,9-dihydro-3H-purin-6-one
International Nonproprietary Names
INN number INN
4435 aciclovir
Synonyms
acyclovir | Zovirax®
Database Links
CAS Registry No. 59277-89-3 (source: Scifinder)
ChEMBL Ligand CHEMBL184
DrugBank Ligand DB00787
PubChem CID 2022
RCSB PDB Ligand AC2
Search Google for chemical match using the InChIKey MKUXAQIIEYXACX-UHFFFAOYSA-N
Search Google for chemicals with the same backbone MKUXAQIIEYXACX
Search PubMed clinical trials aciclovir
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Search UniChem for chemical match using the InChIKey MKUXAQIIEYXACX-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone MKUXAQIIEYXACX
Wikipedia Aciclovir
Comments
Aciclovir is a nucleoside analogue antiviral drug. It is on the World Health Organization's List of Essential Medicines (link to 2015 list).