dorsomorphin

Ligand id: 4907

Name: dorsomorphin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 55.55
Molecular weight 399.21
XLogP 3.51
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-(6-{4-[2-(piperidin-1-yl)ethoxy]phenyl}pyrazolo[1,5-a]pyrimidin-3-yl)pyridine
Synonyms
AMPK Inhibitor, Compound C
Database Links
CAS Registry No. 866405-64-3
ChEMBL Ligand CHEMBL478629
PubChem CID 11524144
RCSB PDB Ligand TAK
Search Google for chemical match using the InChIKey XHBVYDAKJHETMP-UHFFFAOYSA-N
Search Google for chemicals with the same backbone XHBVYDAKJHETMP
Search UniChem for chemical match using the InChIKey XHBVYDAKJHETMP-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone XHBVYDAKJHETMP
Comments
Dorsomorphin is a potent, reversible, selective AMP-activated protein kinase (AMPK) inhibitor [4]. It is an ATP-competitive inhibitor of the catalytic α subunit of the heterotrimeric enzyme.