growth hormone 1

Ligand id: 4943

Name: growth hormone 1

Species: Human

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Classification
Compound class Endogenous peptide in human, mouse or rat
Approved drug? Yes (FDA (1976))
International Nonproprietary Names
INN number INN
239 somatropin
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
GH1 growth hormone 1 Human prepro-growth hormone 1 GH, GHN, GH-N, hGH-N, pituitary growth hormone
Synonyms
Saizen® | somatotropin
Database Links
CAS Registry No. 12629-01-5 (source: Scifinder)
DrugBank Ligand DB00052 (Hs)
Ensembl Gene ENSG00000189162 (Hs)
Human Protein Atlas ENSG00000189162 (Hs)
Search PubMed clinical trials somatropin
Search PubMed titles somatropin
Search PubMed titles/abstracts somatropin
UniProtKB P01241 (Hs)
Wikipedia Growth_hormone_1
Comments
Human growth hormone 1 (somatropin) produced by recombinant technology is an approved drug with the INN somatropin. This has identical 191-amino acid sequence to the endogenous hormone.

Biosimilar drug: The EMA approved the biosimilar named Omnitrope (Sandoz GmbH) in 2006.