IFN-α2

Ligand id: 4960

Name: IFN-α2

Species: Human

Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Interferons
Approved drug? Yes (FDA (1989))
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
IFNA2 interferon alpha 2 Human prepro-interferon alpha-2 alpha-2a interferon, IFNA, IFN-alphaA, interferon, alpha 2, interferon alpha 2b, interferon alpha A
Synonyms
IFN-alpha-2 | interferon alpha-2 | Roferon A®
Database Links
Specialist databases
IMGT/mAb-DB 624
Other databases
Ensembl Gene ENSG00000188379 (Hs)
Human Protein Atlas ENSG00000188379 (Hs)
UniProtKB P01563 (Hs)
Wikipedia IFNA2
Comments
IFN-α2 is a type I IFN. The sequence of the recombinant peptide used clinically and known as interferon alfa-2a, is identical to that of human IFN-α2. Interferon alfa-2a has anti-viral, immunomodulatory and antineoplastic actions. It is on the World Health Organization's List of Essential Medicines (link to 2015 list).