IFN-β   Click here for help

GtoPdb Ligand ID: 4967

Synonyms: Avonex® (recombinant IFN-beta-1a) | fibroblast interferon | interferon beta
Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: IFN-β is a type I IFN. The peptide sequence of the clinically used recombinant protein IFN-beta-1a is identical to that of the endogenous peptide.
Species: Human
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Interferons
International Nonproprietary Names Click here for help
INN number INN
5380 interferon beta
Synonyms Click here for help
Avonex® (recombinant IFN-beta-1a) | fibroblast interferon | interferon beta
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
IFNB1 interferon beta 1 Human prepro-interferon beta IFB, IFF, IFNB, interferon, beta 1, fibroblast
Database Links Click here for help
Ensembl Gene ENSG00000171855 (Hs)
GtoPdb PubChem SID 178101665
Human Protein Atlas ENSG00000171855 (Hs)
Search PubMed clinical trials interferon beta
Search PubMed titles interferon beta
Search PubMed titles/abstracts interferon beta
UniProtKB P01574 (Hs)
Wikipedia IFNB1