carbidopa

Ligand id: 5159

Name: carbidopa

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 5
Rotatable bonds 4
Topological polar surface area 115.81
Molecular weight 226.1
XLogP -0.06
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1977))
IUPAC Name
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
International Nonproprietary Names
INN number INN
3258 carbidopa
Synonyms
Duodopa® | Lodosyn®
Database Links
CAS Registry No. 28860-95-9
ChEBI CHEBI:39585
ChEMBL Ligand CHEMBL1201236
DrugBank Ligand DB00190
GtoPdb PubChem SID 178101851
PubChem CID 34359
RCSB PDB Ligand 142
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Wikipedia Carbidopa
Comments
Carbidopa was originally approved by the FDA in combination with levodopa in 1975. Carbidopa is a noncompetitive decarboxylase inhibitor.