letrozole

Ligand id: 5209

Name: letrozole

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 78.29
Molecular weight 285.1
XLogP 3.01
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1997))
IUPAC Name
4-[(4-cyanophenyl)(1H-1,2,4-triazol-1-yl)methyl]benzonitrile
International Nonproprietary Names
INN number INN
7118 letrozole
Synonyms
Femara®
Database Links
CAS Registry No. 112809-51-5
ChEBI CHEBI:6413
ChEMBL Ligand CHEMBL1444
DrugBank Ligand DB01006
PubChem CID 3902
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Wikipedia Letrozole
Comments
Letrozole is an oral non-steroidal aromatase (CYP19A1) inhibitor, with anti-estrogen action.