practolol

Ligand id: 555

Name: practolol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 70.59
Molecular weight 266.16
XLogP 1.42
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name
N-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide
International Nonproprietary Names
INN number INN
2832 practolol
Synonyms
AY-21011 | ICI-50172
Database Links
BindingDB Ligand 25749
CAS Registry No. 6673-35-4 (source: Scifinder)
ChEBI CHEBI:101380
ChEMBL Ligand CHEMBL6995
DrugBank Ligand DB01297
PubChem CID 4883
Search Google for chemical match using the InChIKey DURULFYMVIFBIR-UHFFFAOYSA-N
Search Google for chemicals with the same backbone DURULFYMVIFBIR
Search PubMed clinical trials practolol
Search PubMed titles practolol
Search PubMed titles/abstracts practolol
Search UniChem for chemical match using the InChIKey DURULFYMVIFBIR-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone DURULFYMVIFBIR
Wikipedia Practolol
Comments
The approved drug practolol is mixture of two enantiomers; (R)-practolol and (S)-practolol. The structure shown here does not specify stereochemistry and represents the mixture.